No idea unfortunately, but definitely not to release pressure. You don’t get air in your brain, it’s all fluid. Outside of the hospital, all the drains drain to somewhere internal, usually the abdominal cavity

Am doctor. Outside of very rare and specific causes of headache, no this wouldn’t fix anything, just put you at risk for infections.

Am a doctor, this wasn’t actually a migraine and is not how migraines happen. Shunts are placed for elevated intracranial pressure, which can occur for a number of reasons, and do cause headaches. But it’s a very uncommon cause of headaches and a shunt will not fix your actual migraines or tension headaches.

Not OP but loss of the Pi results in loss of network connectivity. A headache if you’re home and never doing anything time-critical on the network. A disaster if you or anyone else is dependent on the network for anything time-sensitive (virtual doctors appointment, work call, etc), or you’re away from home and unable to directly VPN to your router to reconfigure DNS settings.

It’s not that we don’t use mode, there are definitely times mode is used. It’s just that mean (and median as well) contain a lot more useful information about distributions that we often care about. For a normal distribution mean, median, and mode should all be identical. So why do we use mean? Because mathematically, the mean is what underpins the formula for the normal distribution, not median or mode, and when you’re talking about doing math with normal distributions mean is the thing to talk about (along with standard deviation).

We use median a lot too, you probably just don’t hear it called median very often. The median is useful in non-normal distributions, and it defines the 50th percentile, so along with the 25%-ile and 75%-ile you’ve got your quartile distributions. We use these all the time to talk about grades in schools, or when we talk about home prices distributions in a given area, or salaries within a given field.

We use mode too, again just by a different name most of the time. Any time you’ve asked “what’s the most common blank” you’re basically asking for a mode. When we talk about “average” income in a country, we’re usually actually talking about median or mode. Favorite animal? Answered as a mode.

You have to use the right statistical tool for your question: unfortunately English doesn’t do a good job of conveying this without math jargon.

All of my encounters with individuals who feel liberal arts are useless and STEM is the way seem to, at their core, feel that way because of earning potential, and I’ve never heard one of them bash Econ/finance/investment as a career path. But 🤷‍♂️

Then no, I don’t agree with this specific implementation of the system, at least the second half. I do think more productive/effective workers should be compensated more. But being a good engineer does not make you a good manager, and the issues associated with promoting an excelling worker into management (a job requiring a substantially different skill set) are so common there’s a name for their inevitable failure, The Peter Principle

I didn’t say it did, but I am a citizen of the USA and the vast majority of my cultural experience and knowledge, and therefore what I can intelligently comment on, are centered on the US.

Well you need to clarify further then. Are you saying we should make the best scientist the president, or the person with the most aptitude for politics and rule to be president? I don’t see how this is functionally different than what I said.

If I was guessing, in general, I think people who advocate for a pure meritocracy in the USA feel the world should be evaluated in more black and white, objective terms. The financial impact and analytic nature of STEM and finance make it much easier to stratify practitioners “objectively” in comparison to finding, for instance, the “best” photographer. I think there is also a subset of US culture that thinks that STEM is the only “real” academic group of fields worth pursuing, and knowledge in liberal arts is pointless -> not contributing to society -> not a meaningful part of the meritocracy. But I’m no expert.

As a general rule, yes. People who are able to better perform a task should be preferentially allocated towards those tasks. That being said, I think this should be a guiding rule, not a law upon which a society is built.

For one, there should be some accounting for personal preference. No one should be forced to do something by society just because they’re adept at something. I think there is also space within the acceptable performance level of a society for initiatives to relax a meritocracy to some degree to help account for/make up for socioeconomic influences and historical/ongoing systemic discrimination. Meritocracy’s also have to make sure they avoid the application of standardized evaluations at a young age completely determining an individual’s future career prospects. Lastly, and I think this is one of common meritocracy retorhic’s biggest flaws, a person’s intrinsic value and overall value to society is not determined by their contributions to STEM fields and finance, which is where I think a lot of people who advocate for a more meritocracy-based society stand.

You’re generalizing a specific phenomenon, and incorrect. Acid-base reactions only very rarely produce gases. The reactions produce heat and water, only in the case of bicarbonate being a base is a gas produced. This is because carbonic acid forms, which spontaneously decays into carbon dioxide. This is not a universal acid-base phenomenon. Soaps should not cause fizzing with vinegar.

All remote based typing is awful, T9 included. I can’t speak for everyone, but I can type with swipe gestures on a virtual keyboard via remote faster than I can input T9 text. I’m unaware of any stock remote for a device with a full keyboard. I would argue Apple has text entry perfected at least as well as any other major manufacturer. You have virtual keyboard entry, solid voice-to-text, and it can be configured to push a notification to your iOS device when you enter a search bar which will auto-open to the remote app and pull up the keyboard. Because of this feature passwords can also be autofilled from Keychain to make logins easier.

You may personally prefer T9, but I’ve never seen anyone in the last decade input anything into a TV via T9. And you’re asking why it doesn’t have voice input, when it does. You admit to having never used an Apple TV yourself. I hate the idea of app-only interfaces features, but this isn’t a case like that. Maybe you should understand the features of a product before you call it “fucking stupid”.

You’ll have to strike a balance between security and ease. Your two major options are reverse proxy and VPN (Tailscale is one option for VPN)

For reverse proxy, you functionally open the app to the internet. Anyone with the correct web address can access the login page. This is inherently less secure than VPN, but not irresponsibly so. Beyond the reverse proxy itself, you’ll also have to learn how to configure an HTTPS certificate to increase security since it will be open to the internet.

For VPN, every user you want to be able to access the service has to be tied into the VPN and have the VPN running throughout their access. Tailscale is arguably the easiest way to configure a VPN right now, as you won’t have to manually deal with VPN configuration files for every device. VPN use will functionally make it like you’re on your home network. VPN access to your network should not be given to tons of people if at all possible.

I would like to point out, the NYT is a reputable news site but cannot even remotely be trusted with medical information/recommendations. I can’t tell you the last time I read a medical news piece from any source (and the NYT is the primary place I get my news) that I couldn’t read it and say “well that’s a gross oversimplification” or worse “this is blatantly misrepresenting the scientific author’s conclusions”. Holding up the NYT as a source of medical/scientific truth is just demonstrating how scientifically illiterate you really are.

You’re citing forum posts to discussions (with some evidence mentioned within) to support this supposition that doctors are horribly informed and out of date. But I’d like to point out that this is being vastly overblown, and even a 5-10 year out-of-date medical professional has immensely more knowledge and safe ability to recommend therapy than a layperson. I can’t pretend to know the credentials of the individual you’re responding to, but they’re clearly well versed in clinical infectious disease based on their comments, and you’re not supporting your position by citing a forum instead of the actual primary literature that supports your position.

Section 2, first paragraph. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956183/

At their core phages are viruses, there is no reason to expect the host immune system to not recognize them as foreign and attempt to eradicate them outside the GI tract, where most serious infections occur. The GI tract, skin, and to some extent the lower UG tract will likely tolerate these through mechanisms we tolerate colonizing bacterial flora, but colonization, even with antibiotic resistant organisms, is not a primary indication for empiric treatment for eradication. In fact there are some studies that attempting to sterilize the UG tract in colonized asymptomatic women promote symptomatic UTI.

These colonizations become problematic when growth becomes unchecked and infection develops, or they seed infection into another compartment. There is no reason to think something as foreign as a bacteriophage wouldn’t be recognized as foreign in a sterile space (kidneys for pyelonephritis, liver abscess from migrated gut flora, endocarditis, etc) where these serious infections occur.

This ties in nicely with your suggestion of phage cocktail therapy. Yes, that can expedite the delivery of phages, however excessive use of phages could result in anti-phage antibodies, limiting future treatment in a method similar to the development of anti-drug antibodies in epoeitin analogues, insulin therapy, antivenin, and anti-inflammatory antibody therapies like adalimumab (Humira)

Yup, it’s hard to have a good discussion about the changing tides in ID without feeling like you’re causing a bunch of backsliding and non-compliance. I think being honest with people that the data is generally poor about how we select durations is the moral thing to do. But I do want you to just take your damn antibiotics as prescribed instead of going rouge because you heard “shorter is better” and your pneumonia recurring.

Yes, it covers intestinal colonization with MRSA. Unfortunately Staph aureus is an uncommon GI pathogen, and the majority of detrimental infections secondary to MRSA come from skin-flora translocation to produce surgical site infections/blood stream infections, as well as translocation from the nares into the lungs to produce pneumonia. We thankfully have another method of nares decolonization. While metallobetalactamase producing Pseudomonas is mentioned as well, I have a very low suspicion that FMT would be useful for resistant Pseudomonal pneumonia or diabetic foot infections/osteomyelitis. FMT certainly has a role to play in ID, particularly for enteric gram negatives and VRE within the alimentary canal, but is not a cure-all for antimicrobial resistance.

Hello all, I’m a pharmacist and 4th year medical student with a passion for antimicrobial stewardship and infectious disease. Just wanted to share my overall thoughts on the article.

The author’s point of “finding out if you really need an antibiotic” is honestly one of the central issues in modern antimicrobial resistance coming from two fronts: patients who demand an antimicrobial for a non-indicated reason, and doctors who for various reasons excessively prescribe antibiotics. I could wax on this for hours, but at its core, the single most important thing we can do to decrease antimicrobial resistance is decreasing total antimicrobial exposure. That means fewer prescriptions for shorter courses of narrow-spectrum antibiotics. Unfortunately every bit of this requires more buy-in from patients and more work from clinicians.

To go along with my point above, asking your doctor to make sure you’re getting the shortest possible duration is the single best thing you as a patient can do to help with these issues (other than just not demanding antibiotics if your doctor says no, but that’s a low bar). The key word here is ask though. There’s a huge amount of clinical experience and evidence that is used to determine when it is safe to stop antibiotics. And as much as I believe in patient autonomy and educating my patients, frankly antibiotic selection/course duration is not something the general public is capable of independently making decision on. Ask your doctor, and take what they prescribe for how long they’re prescribed for, and if you have issues then call them to discuss it.

With regards to probiotics, it’s an interesting topic that we don’t have a ton of great data for and physicians are fervently behind or against them in my experience. The fact is we just don’t know enough about them, and most aren’t regulated well enough to give good information about them. Interestingly, there was a recent study which suggested higher rates of central line infections with the organisms in the probiotics in individuals given probiotics while they had a line in place.

Lastly, I think I have to disagree with Dr. Blaser. Medicine doesn’t overvalue antibiotics. We certainly underestimate their risks, but antibiotics are some of the most effective and life-saving medications we as a species have ever developed. Countless lives have been saved solely from their development, and very very few therapies have a NNT as low as appropriate antimicrobial therapy. They truly are astonishingly good medications when they are indicated. The issue is simply prescribing them when they aren’t indicated, which is a big part of why we’re in the mess we’re in, and is in large part driven by underestimating the risks they pose.