Not sure what’s up with Nature’s website on your end, but here’s the link that’s working for me to access the paper, which was published today (10-3-25): https://dx.doi.org/10.1038/s43018-025-01054-6

Nonetheless, a paper from 6 years ago studying a receptor found on almost half of immune cells should have more current information available by now, if not already. In science, we build on the shoulders of giants and try to expand on the knowledge they helped us understand. Additionally, the older study examines SLAMF6’s function across health and disease, so it’s much more generalized. The new study aims to provide additional context for the earlier findings and focuses on acute myeloid leukemia in particular. I have a PhD in immunology, and it’s astonishing how little we actually understand about the subject. All in all, we understand the ocean better than the immune system, even though there’s more we don’t know about the ocean than we do. Even crazier is that most of our current understanding in immunology is actually for a rat’s immune system and not humans! But you’re not wrong to be cautious, all research papers should be read with a healthy amount of scrutiny. A wise man told me in undergrad that half of what we’d cover in the course would be incorrect, we just don’t know which half.

SoundCloud is pretty cool, especially when compared to Spotify. I’ve been really liking the https://sc.maid.zone/ SoundCloud frontend recently, makes it more private and you can download the songs on the same page you can listen to them. But all in all, it really just comes down to your opinion regarding if you should talk positively about it.

Yep, cellulose is a beta pleated sheet, unlike carbs/sugars, which are alpha helices. We’re always ready to breakdown the alpha helices form of sugar, but due to the molecular structure of cellulose, we need help. This is were these enzymes come in from our microbiome. All this also ties into how in Western countries, most folks tend to be unable to breakdown cellulose due to the lack of the specific bacteria in our biome capable of producing this enzyme. However, in African and Asian countries, these bacteria are common place, so these cultures have been able to digest cellulose for ages!

Well said!!

For anyone new to the Linux world, I can’t recommend Learn Linux TV enough. He has a video walking through this exact process, here’s an Invidious and YouTube link for it.

As far as dual booting goes, issues can arise after updates. I recall this happening a few months back due to a Windows update. So just be aware of this possibly happening down the road. I need Windows for work at times too, but I strictly use a VM. I’ve hated Microsoft since Windows 8, their amount of user tracking is bonkers and a big part of why I just use a VM. This is just food for thought though.

The add-on’s are solid. They have an elaborate curated list, plus you can access any of the mobile extentions by just searching for em.

Obsidian isn’t FOSS, but two fantastic replacements are Standard Notes and Notesnook.

A great paint option I don’t see listed is KolourPaint, plus Kdenlive for video editing. For audio editing, Tenacity is the better choice over Audacity. It’s an Audacity fork made after some questionable privacy policy changes.

CryptPad is an awesome Google Doc’s replacement, but Libre Office is actively working on their version too.

For your security section, adding some encryption software would be smart. Both VeraCrypt and Cryptomator are amazing. Also, Bitwarden/Vaultwarden are solid password manager alts for KeePassXC, with Vaultwarden being self hosted.

Here’s a great site for all sorts of Lemmy clients.

As far as Linux laptops go, System 76’s Darter Pro is also a solid choice. Tuxedo is probably System 76’s biggest competition, as they offer very comparable laptops. Their InfinityBook Pro is a great computer. Frameworks, Slimbook, and Star Labs are all also worth a mention.

Definitely recommend replacing Fennec with IronFox on mobile, it’s a fork of Mull, so it’ll be a solid privacy upgrade!

Exactly! This is a big reason why all corporate media still endlessly states Hamas killed 1200 Israelis 10/7, while it’s now known Israel used the Hannibal Directive and were responsible for at least a few hundred of the deaths. This was even stated by the man in change of the Israeli military at the time too…

A virtual machine is the move, I’ve had a great experience with virt-manager. Strongly recommend debloating the windows VM if Microsoft is getting on your nerves. Here’s my go to software: https://github.com/raphire/win11debloat

Worksorks on both windows 10 & 11. It’ll allow you to remove telemetry, tracking, and even software Microsoft prevents you from uninstalling. I just can’t get it to remove Edge. But MentalOutlaw has a fantastic walk through of the process on his YT channel if you want some guidance with the debloating process.

Sure, maybe on paper…but check this out: https://scheerpost.com/2025/02/01/did-a-trump-executive-order-just-cripple-the-global-us-regime-change-network/

Regardless, why is the only aspect of USAID which was “forked” into a Trump approved department specific for coup’s? Makes you think which, with nothing but love, is something it seems you should do more of when it comes to US policy.

The fact USAID is supposed to provide aid to people around world in need of help, yet this aid is just a smoke screen to cover for the funding of coup’s on governments which opposes the US empire…

It’s not just USAID. The BBC is actually funded by two branches of the US government.

Last year, the US State Department gave BBC Media Action £280,000.

The group says it used the $$$ to reach 100 million people in 24 countries with its programmes.

After covering the BBC’s public relations response, the article then goes on to say:

That sounds nice, of course. But when you’re aware of the role USAID has played as the ‘friendly face’ of US imperialism, more scrutiny of BBC Media Action is essential.

What I took away from it is that since the BBC is affiliated with this blatant US corruption, regardless of directly or indirectly, the specifics regarding the association needs to be known by the public.

I’ve been really liking the KISS Launcher, it’s power is in it’s simplicity. It also looks relatively comparable with Smart Launcher. What’s super impressive about the KISS Launcher is that 93% of users that try it for a week are still active users after 3 years! So definitely worth a gander for sure.

You’re server’s #3 when it comes to monthly active users too!

When you sort by monthly active users, this is what you get:

What really jumps out to me is the fact .ml’s active users equals the total users. Not too sure what to make of it. I’d assume the mod’s delete nonactive accounts after a set amount of time or it’s just relatively small based on total users but everyone’s visiting at least once a month.

I hear what you’re saying, but I wanted to point out that any living organism is built from the same 20 amino acids, which are put together based on a blueprint (aka DNA). A string of amino acids is called a polypeptide, which is also known as a protein. But both dogs and wolves are omnivores, it’s a common misconception to think they’re carnivorous. Cats on the other hand are carnivorous creatures.

Additionally, it is not necessarily true that carnivores are more intelligent than omnivores or herbivores as a result of their diet. Instead, predators and prey are in a contest of brain size relative to body size. While carnivores and omnivores have more potential opportunity to develop intelligence, they’d have to be a social species for that to occur. So relative brain size and intelligence aren’t directly associated with diet, but more so a result of social structures and genetics.

Not exactly, Homo erectus and Neanderthal’s both ate meat. The consumption of meat by Homo erectus was associated with a reduction in the size of the gut area due to consistently incorporating animal foods into their diet. Neanderthals were known to be skilled hunters as well. The biggest difference between us and our more recent ancestors is the truncation of a GTPase gene in our DNA, which led to the ability to have neurons grow on top of one another. Previously, neuron growth would be stopped when a neuron came into contact with another. So that’s without question the biggest genetic feature that sets us apart.

Right! But, if you zoom out, it’s not exactly too wild. Ground squirrels have voles beat in size and they have habitat overlap with both living underground. Additionally, dietary shifts give animals the flexibly to respond to changes in the environment plus foraging risks and opportunities. It’s been known since the early 2000’s that squirrels can supplement some of their diet with insects or bird eggs/baby birds. Knowing this, it starts to make a lot more sense ground squirrels would hunt voles, as the environment is rapidly changing, they’re known to already hunt a bit, and voles could be their annoying neighbor.

With the deterioration of our ecosystem, it makes sense lifespans will decrease. But this one seems fishy. At the turn of the century, which preceded the discovery of antibiotics, the average life span was 32. Back then, childbirth was actually dangerous and the amount of kids dying under 3 years old was wild. These were the primary reasons for the 32 year average lifespan. Which means 26 in todays world is almost certainly a sign of fowl play…