• Sir_Kevin@lemmy.dbzer0.com
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      5 months ago

      EDIT: dunno why, but because Beehaw, I can’t actually see the comment below. So I’ll answer here…

      Beehaw defederated from a lot of the bigger instances because someone hurt their feelings or whatever. So now you miss out on the majority of lemmy content including comments. I would suggest creating an account with a different instance so that you can experience the entirety of the community.

      • apotheotic (she/her)@beehaw.org
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        5 months ago

        Beehaw has defederated from instances they felt were not meeting a minimum standard of moderation and healthy, good faith discussion. Beehaw’s whole shtick is to maintain a platform where its users can be(e) kind and expect others to behave similarly.

        It is genuinely baffling to me how people can see beehaw curating their instance this way and go “feewings” and “beehaw bad”.

        • Sir_Kevin@lemmy.dbzer0.com
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          5 months ago

          If people want to be part of a limited community that’s fine and well. The issue I have is that a lot of people joining lemmy don’t know what beehaw is about and join it just because it’s a name they’ve maybe heard of. Then they’re completely unimpressed by lemmy, not knowing they’re only part of a fraction of the federation. Next thing they’re back on reddit or whereever.

          Also, as someone with access to the majority of lemmy instances, I’ve only ran into maybe a handful of assholes on here. I’m really not sure what beehaw is trying to shelter it’s users from. It’s easy enough to block someone on the rare occasion.

          • apotheotic (she/her)@beehaw.org
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            5 months ago

            Its incredibly difficult to join beehaw without knowing what its about. When you apply to join they explain what it is and ensure that you’re actually, like, on board with the mission. I can understand the sentiment of users finding themselves underwhelmed and leaving if they don’t understand why.

            As someone with accounts on other instances, I’ve definitely encountered far more bigotry and bad faith arguments off-beehaw than on-beehaw. For some people, which would appear to include you, encountering the asshole and blocking and moving on is sufficient, and that’s fine and awesome for them. But for others who may be part of marginalised communities or particularly vulnerable, the bubble of safety and curation that beehaw offers is so tremendously valuable.

            • Sir_Kevin@lemmy.dbzer0.com
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              5 months ago

              Ok, sounds like they’ve made it a lot more clear since the reddit exodos which is the last time I’ve had any interaction with beehaw. That’s good then.

    • protist@mander.xyz
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      5 months ago

      Type I diabetes has absolutely nothing to do with weight, it’s a disorder of the pancreas that’s mostly genetic. The rates of all forms of diabetes taken together in China and the US are almost the same. I’m sorry if this science flew over your head yo

      • HumanPenguin@feddit.uk
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        5 months ago

        Its worse the that. Many think now it is reversed. As T2 is a resistance to insulin. And without insulin you cannot gain energy from your diet. It is now commonly accepted that those prown to t2 diabetes are often forced to eat due to the body gaining less energy from food.

        So being genetically prown to to can lead to weight gain prior to diagnosis. Rather then weight gain leading to to t2d.

    • filoria@lemmy.ml
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      5 months ago

      Citing MBFC without supporting evidence is lazy and actively harms discussion in favour of policing “wrongspeak”. I respect it.

  • Etterra@lemmy.world
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    5 months ago

    What are the odds we’ll get this in America in the next 20 years? Or that insurance will cover it? I mean we live in for-profit medical hell. They actually have weight loss drugs that like 7/10ths of Americans need, but a month’s worth cost over $1,000 out of pocket. Insulin is already stupidly overpriced and there’s no financial incentive to cure it, so why would they? The insurance and pharma companies aren’t in the business of helping people. If they were there be non-proffits (for a start). Instead they get as much federal subsidy money as possible and then still charge $1,000 a month that insurance might cover if you’re lucky or rich enough to even have any that’s worth a damn.

    So yeah, cool story, but here in America this won’t make any difference. Maybe in 50 years it’ll be affordable, we’ll see.

  • SeattleRain@lemmy.world
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    5 months ago

    Why is everyone online so incredulous of this breakthrough? Is it just Sinophobia or are there reasons to doubt Chinese medical findings?

    • ILikeBoobies@lemmy.ca
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      5 months ago

      There’s reason to doubt all sensationalist medical headlines

      But this is 1 patient, no long term effects studied (just doesn’t need insulin injections), and hasn’t been validated

      Nothing to do with China

    • Raiderkev@lemmy.world
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      5 months ago

      Their Covid vaxx was trash. My aunt’s friend was a UAE resident, and got sinovac Covid shot. He later caught and died from covid, so that’s my anecdotal reason not to trust it, but if it is true, this would be a great thing.

      • ɔiƚoxɘup@infosec.pub
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        5 months ago

        Right? Media and science do not play well together. I can’t count the times I’ve seen amazing new discoveries or cures heralded by the media that never come to fruition because they were only ever just theoretical to begin with or they were never replicated by any other researcher.

    • zephyreks@lemmy.mlM
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      5 months ago

      Lemmy is a news aggregator. Why wouldn’t you find out about an early-stage clinical trial on Lemmy?

      Any such treatment, even if it works, would take decades to pass through the various approval stages before being released to the public.

      • UmeU@lemmy.world
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        5 months ago

        The headline isn’t ’early stage clinical trial starts the multi-decade process of developing a cure for diabetes’… the headline reads ‘diabetes has been cured’

        Alls I’m saying is that if the headline as written were true, we would be hearing it from all news sources at once, not just some single post on a somewhat obscure news aggregator.

    • 𝘋𝘪𝘳𝘬@lemmy.ml
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      5 months ago

      If this were true you wouldn’t hear from this at all.

      A permanent cure isn’t something that is wanted by pharma companies. It’s better for them to have something that keeps patients alive and that they need regularly and that is expensive but cheap enough for them to get.

      • threeduck@aussie.zone
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        5 months ago

        But why wouldn’t a rival company just start up and sell the cures? Not all pharma companies sell insulin.

        • 𝘋𝘪𝘳𝘬@lemmy.ml
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          5 months ago

          Because then the rival company would also go out of business. The pharma industry is not about absolute cure but about continuously selling things - like all industries do. Medicine that cures you entirely and is not needed afterwards forever again is nothing the pharma industry wants.

          • AbsentBird@lemm.ee
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            5 months ago

            Exactly, that’s why we’ll never have a vaccine for something like polio, it’s too profitable to make and sell iron lungs.

            • BarbecueCowboy@lemmy.world
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              5 months ago

              You joke, but that’s actually a really interesting story. Jonas Salk, the developer of the first polio vaccine was adamantly against even patenting it and claimed that it ‘belonged to the people’. There is some potential controversy there, but we mostly just think he was a pretty great dude. Dude’s a fucking hero regardless.

              I get the analogy you’re trying to make, but maybe want to switch to something else.

              • CileTheSane@lemmy.ca
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                5 months ago

                I get the analogy you’re trying to make, but maybe want to switch to something else.

                Like any other vaccine?

              • AbsentBird@lemm.ee
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                5 months ago

                I don’t really see how that goes against it. If anything it shows that some people will totally disregard profit in favor of bettering humanity. See also: the patent for insulin.

      • UmeU@lemmy.world
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        5 months ago

        How would reading Cell Discovery increase my chances of hearing about a cure to one of the world’s most pervasive afflictions on some obscure Lemmy post, and more puzzling, how would reading Cell Discovery make it more likely that some wild medical claim with far reaching implications would both be true and also absent from every other news source? What kind of magic does this Cell Discovery have?

    • shameless@lemmy.world
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      5 months ago

      I mean it is… They could literally have a cure that they can sell to millions of people around the world, as well as millions more who will contract diabetes in the future.

      I don’t understand this conspiracy and companies don’t want cures. I can understand scepticism around pharmaceutical companies for all the awful shit they’ve done, but it doesn’t mean that scientists and researchers will never be able to produce cures.

      • matcha_addict@lemy.lol
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        5 months ago

        Pharma investors have a solid position and are already racking big profits from the continuous model of insulin treatments. A cure would be a detriment to their profits, so it’s not something they’re interested in funding.

        No investor nowadays thinks a one-time-payment product is worthwhile. We’re already way past that.

        This isn’t to mention that if you were an investor who decided you wanted to go ahainst that, that the other mega corporations (with more funds than most of those 5% individuals) wouldn’t engage in anti competitive practices to shut you down. Many companies had good products but still ultimately failed. I mean hell, the boeing events have shown us the lengths a corporation is willing to go to protect its profits, and that’s just what we heard of.

        Unfortunately capitalism does not allow innovation to flourish like many of us were taught to believe.

      • Valmond@lemmy.world
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        5 months ago

        Yeah and there are other parts of the world where researchers search for stuff like this too. If it works it will being fame and money to the inventors and then the drug exists and can ve sold.

      • Asafum@feddit.nl
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        5 months ago

        I don’t exactly subscribe to the conspiracy but I can understand it as it’s related to “planned obsolescence.” Companies don’t want to sell you a quality product that will last “forever” they want to sell you something that’s just good enough to work for a bit, but will absolutely break or be replaced very soon so you become a repeat customer as opposed to a one time customer.

        The same logic applies here with the medication, why would they sell something once even if there were new future customers, if they could instead have everyone on a “subscription” of sorts?

        The conspiracy exists because we see it play out in every other facet of our society/economy. Everything is becoming a subscription, you don’t own anything, every product a corporation makes is almost complete garbage, etc… I’m not sure I believe it 100% but I wouldn’t in the slightest bit be surprised to find out that actually was the case.

        • pingveno@lemmy.ml
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          5 months ago

          There is no grand secret conspiracy. Why? The more people involved in a conspiracy, the more likely it will leak out. A conspiracy between two people may never get it, a conspiracy between a hundred people will have someone slip up in a few years at most, but an international conspiracy involving millions of people with disparate interests wouldn’t stay secret for a second.

          What we’re seeing isn’t a conspiracy as such. It’s a conversation happening in the open about “business models” and “revenue streams”. It’s also based on customer expectations. There are definitely markets out there for the repairable, buy it for life goods, but there’s just not nearly as big as the customer who upgrades their phone every two years. But obviously that’s going to be different for diabetes. Reliably being able to repair pancreatic cells would be huge. If the companies selling insulin tried to internally stifle research to avoid cannibalizing their insulin business, other companies have an enormous incentive to take a crack at it.

  • tooLikeTheNope@lemmy.ml
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    5 months ago

    Oh crap! If this is true then avoid spending a ton of money in insulin supplies each year could give an actual reason to politicians for reducing the healthcare state budget, which they normally do at every occasion just without a proper explanation… I don’t know if my mind is ready for rationality in politics /s

    • Ragnarok314159@sopuli.xyz
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      5 months ago

      Remember, it was the Chinese labs that also reproduced the room temperature super conductor experiment a few years ago and also found their own material…and then it all turns out to be complete bullshit.

      One patient doesn’t mean anything. It’s great if it’s real (having worked directly with China for engineering, I have zero faith this is even a real thing) but there is a lot of reason to doubt at this point.

  • werefreeatlast@lemmy.world
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    5 months ago

    Mexico developed the cure many centuries ago. First you tie the person to a large log. Then smaller logs are placed around the person. Oh man I forgot what you’re supposed to do with the tinder and matches. But some research could help. It cures all sorts of stuff. Not good for burns or preexisting death from what I gathered.

  • DarthYoshiBoy@kbin.social
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    5 months ago

    So this is neat. Potentially life changing for some type 2 diabetics, but that depends because some t2 diabetics are not failing to make enough insulin, they’re just no longer sensitive to it at a level that makes it functional for them. I suppose it’s possible that this therapy could cause them to grow enough islet β cells to overcome their lack of sensitivity, but (and I’m a type 1, not a type 2, so maybe my info is incorrect here) that lack of sensitivity can grow with further exposure to insulin making this a stop-gap at best for those cases absent other therapies.

    …and with all of that said, being able to regrow islet β cells has never really been the problem for type 1 diabetes. You can regrow all the islet β cells you’d like and it’s not going to cure the underlying immune disease that has caused your immune system to kill off all of your islet β cells to begin with. Unless you can figure out why t1 diabetes causes one’s own immune system to go psycho killer on their islet β cells, you’ve done nothing to “cure” diabetes. Without being able to suppress that impulse for your immune system to murder your own cells, any ability to replace the islet β cells is going to be temporary at best, and probably a waste on the whole.

    My brother in law is a “cured” type 1 diabetic, by virtue of his having had a kidney replacement and being on immune suppressing drugs for that. Since they were already replacing the kidney and he was going to have to take immune system suppression medications for that, they also just replaced his pancreas at the same time and the suppression of his immune system has allowed the new pancreas to thrive and continue to make insulin. Easy-peasy. The only trade-off is that he is super immunocompromised and can be killed by common colds, so not a great strategy in general.